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Impresionante hallazgo en el cerebro de los ratones podría aportar a la investigación sobre el autismo

Published Sat, 22 Feb 2025 04:23:54 GMT

Un nuevo circuito cerebral que se desarrolla en el córtex durante una etapa temprana del desarrollo embrionario y que puede aportar nuevos conocimientos sobre los trastornos del espectro autista. Ese es el resultado de un nuevo estudio realizado en ratones que publica este lunes Cell.El equipo, encabezado por el Instituto de Oftalmología Molecular y Clínica de Basilea (IOB) comprobó que al alterar genéticamente ese circuito recién descubierto se produjeron cambios similares a los observados en los cerebros de personas con autismo.“Comprender el desarrollo detallado de los tipos de células y circuitos de la corteza cerebral puede aportar información importante sobre el autismo y otras enfermedades del neurodesarrollo”, afirmó Botond Roska, del IOB y uno de los autores del artículo.El autismo se asocia desde hace tiempo a circuitos defectuosos en el córtex, que es la parte del cerebro que gobierna la percepción sensorial, la cognición y otras funciones de alto orden, el cu...

Liverpool ends barren run by thrashing Leeds 6-1 in EPL

Published Sat, 22 Feb 2025 04:23:54 GMT

LEEDS, England (AP) — Liverpool won for the first time in five English Premier League games after thrashing Leeds 6-1 on Monday.Liverpool hadn’t tasted victory in more than six weeks, since routing Manchester United 7-0.But after Cody Gakpo’s opener and Mohamed Salah’s quickfire addition for a 2-0 halftime lead, Liverpool tore apart Leeds in the second half. Salah and Diogo Jota finished with a pair each, and Darwin Nunez came off the bench to score late.Leeds halved the deficit two minutes after the break when Ibrahima Konate was caught in possession by Luis Sinisterra, who lifted his effort over goalkeeper Alisson to make it 2-1.But the Leeds defense collapsed in familiar fashion, suffering consecutive heavy home defeats eight days after losing to Crystal Palace 5-1. Leeds has conceded 60 league goals, more than any other side,Liverpool remained eighth in the standings, two points behind Brighton. Leeds’ survival hopes were dealt another big blow by staying...

Juvenile injured in shooting outside Green Valley Ranch Airbnb

Published Sat, 22 Feb 2025 04:23:54 GMT

DENVER (KDVR) -- Denver police are still working to learn what led up to a shooting that left one juvenile in critical but stable condition on 48th Place in Green Valley Ranch. "We did call 911 two or three times," one neighbor, who wanted to remain anonymous stated Sunday. FOX31 and Channel 2 reached out to the owner of the home where DPD said a large gathering was happening. The owner of the home stated he had rented out the home short-term via Airbnb. “There were a lot of teenagers. I would say anywhere between 15 to 19 years old," the neighbor said. Green Valley Ranch violence spiked 50% in 2022 The homeowner also stated he is deciding if he will take the Airbnb listing down because he wants neighbors in the area to feel safe.“We started hearing gun shots and its turning normal now," the neighbor said. What led up to the shooting is still under investigation.

Quest Workspace is the perfect hybrid office with lots of treats

Published Sat, 22 Feb 2025 04:23:54 GMT

We mostly to using the word hybrid to talk about car models, but now, many of us have hybrid work models. If you’re a little tired of all the distractions at home, we know stylish workspaces where the amenities make work feel more like fun. If you can actually remember to work.Oh, ok. Well, I guess I’ll just go to Quest Workspace then.Laura Kozelouzek: “When you combine a great stylish workspace with a lot of different amenities that allow you to work the way you want. You can not only be successful but you can also have a great time doing it.”Where the opportunities are just as hot as the unlimited coffee.Laura Kozelouzek: “You can be a start-up that is literally just getting your business kicked off the ground or, you can be a Fortune 100 company, we’ve got some of the you know, the top names in business in our spaces.”To get the tea, I met Quester Mariana Niro at their Brickell location.Mariana Niro: “The real estate market in Miami...

City Furniture, Habitat for Humanity team up for Eco-friendly deliveries

Published Sat, 22 Feb 2025 04:23:54 GMT

With Earth Day right around the corner, City Furniture and Habitat for Humanity are teaming up to make environmentally friendly deliveries.From April 21 to April 23, customers in Broward and Palm Beach counties will be able to shop and donate to Habitat for Humanity at the same time. Once you buy an item from City Furniture movers will deliver it and during the delivery will pick up your old furniture and take it to donate to Habitat for Humanity for you.“It really is truly a pain point for our customers, ‘What do I do with my old furniture?’ We’re gonna go into their homes, help take any of their future out and bring it to Habitat to donate on their behalf,” said City Furniture CEO Andrew Koenig.The product that City Furniture delivers to Habitat for Humanity is resold and that finances their availability to build affordable homeownership for families across the region.Last year, City Furniture saved over 50,000 pounds of furniture from going into land...

Matzo Mingle offers Jewish singles somewhere to meet and network

Published Sat, 22 Feb 2025 04:23:54 GMT

“Let my people go” is a very famous phrase in Jewish history. Let my people go party. That’s a good one, too. Jewish singles have a brand new chance to meet up in the Magic City after a hard day’s work. It’s so cool, even your mother would approve.Jewish professionals looking for unleavened love just might find it at Matzo Mingle.Brandon Sirota: “It’s a young after-work Jewish singles networking and dating event.”Matzo Mingle is the smaller version of Matzo Ball, the yearly big-time bash that happens each December.Brandon Sirota: “Matzo Ball is the nation’s largest and number one dating event and holiday party all across the country, so we’ve been going around for about 35 years now at the hottest clubs in the country, especially here in Miami at LIV Nightclub.The first-ever mingle goes down at American Social in Miami — a very fitting site to kick off this monthly soiree.Brandon Sirota: “Here in Miami peo...

Friends, family of Martin Richard among 2023 Boston Marathon finishers

Published Sat, 22 Feb 2025 04:23:54 GMT

Friends and family members of Martin Richard were among the thousands of people who crossed the Boston Marathon finish line on Boylston Street Monday, marking an emotional day 10 years after Martin was killed in the marathon bombing in 2013. Martin’s brother, Henry, ran alongside several friends with the family’s MR-8 Foundation. They then met Henry and Martin’s mom as well as their sister Jane at the finish line. “It’s a very emotional race for me, my family, for my friends — Martin’s friends, so I definitely thought of him the whole way,” Henry said of the marathon and his brother. “Running as one and running as a team really kept us going the whole way,” he continued. “It was a beautiful thing.”Martin Richard was the youngest victim killed in the bombing. As runners hit the course, the bombing and its victims were also on the mind of Boston Bruins legend Zdeno Chara, who ran his first Boston Marathon this year after a championship career on the ice.“I’m ...

Santos announces 2024 reelection campaign for New York congressional seat

Published Sat, 22 Feb 2025 04:23:54 GMT

(CNN) — Embattled GOP Rep. George Santos announced Monday he will seek reelection in 2024 to represent New York’s 3rd Congressional District, defying the calls from some Republicans on Capitol Hill and in his district to step aside.“I’m proud to announce my candidacy to run for re-election and continue to serve the people of NY-3,” Santos said in a statement announcing his candidacy.Santos faces long odds. He has lied extensively about his resume, education and family background and now faces federal and local investigations into his finances. As a result, senior Washington Republicans have told members of their party that they will not let Santos be the nominee for his seat.Still, Santos has maintained that he has no intention of stepping down early, and he filed paperwork in March formally declaring his 2024 candidacy.House Speaker Kevin McCarthy let out a laugh when asked by CNN Monday if he would support Santos’ reelection ...

Teen dies after being hit by car in Middleton driveway 

Published Sat, 22 Feb 2025 04:23:54 GMT

A 15-year-old girl who was hit by a car in a driveway in Middleton last week has died, officials announced on Monday. The incident happened last Monday off Meadowlark Farm Lane around 2:20 p.m., according to police. The girl was flown to Massachusetts General Hospital, where officials said she succumbed to her injuries on Sunday. In their update this week, Essex County District Attorney Paul Tucker and Middletown Police Chief William Sampson said the driver of the car that hit the girl stayed at the scene and has cooperated with authorities. Citing an initial investigation, officials said the incident appeared to be a tragic accident. SKY7-HD flying over the scene last week captured images of a car believed to be involved. A device that appeared to be a jack could be seen underneath the car before the vehicle was towed away.Police said officers responding to the scene rushed to help the victim. Of them, officials said one officer suffered a leg injury and was taken to...

Man charged in front-door shooting of Black teen Ralph Yarl

Published Sat, 22 Feb 2025 04:23:54 GMT

By MARGARET STAFFORD and JIM SALTER (Associated Press)KANSAS CITY, Mo. (AP) — An 84-year-old white man in Kansas City, Missouri was charged Monday with first-degree assault for shooting a Black teen that mistakenly approached his house while trying to pick up his siblings.Prosecuting Attorney Zachary Thompson said at a news conference that there was a “racial component” to the incident last Thursday night when Andrew Lester twice shot 16-year-old Ralph Yarl, who is recovering at home after being released from the hospital. But nothing in the charging documents says the shooting was racially motivated, Thompson clarified.“We understand how frustrating this has been but I can assure you the criminal justice system is working and will continue to work,” Thompson said at a news conference.The shooting outraged many in Kansas City and across the country. Civic and political leaders — including President Joe Biden demanded justice. Some, including lawye...